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1

The coming of age of de novo protein design

Huang, Po-Ssu, Boyken, Scott E., Baker, David

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 5.21 MB

english, 2016

2

Exploring the repeat protein universe through computational protein design

Brunette, TJ, Parmeggiani, Fabio, Huang, Po-Ssu, Bhabha, Gira, Ekiert, Damian C., Tsutakawa, Susan E., Hura, Greg L., Tainer, John A., Baker, David

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 11.96 MB

english, 2015

3

Protein structure determination using metagenome sequence data

Ovchinnikov, Sergey, Park, Hahnbeom, Varghese, Neha, Huang, Po-Ssu, Pavlopoulos, Georgios A., Kim, David E., Kamisetty, Hetunandan, Kyrpides, Nikos C., Baker, David

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 2.20 MB

english, 2017

4

Adaptation of a fast Fourier transform-based docking algorithm for protein design

Po-Ssu Huang, John J. Love, Stephen L. Mayo

Journal:

Journal of Computational Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 333 KB

english, 2005

5

High-resolution structure prediction of a circular permutation loop

Bruno E. Correia, Margaret A. Holmes, Po-Ssu Huang, Roland K. Strong, William R. Schief

Journal:

Protein Science

Année:

2011

Langue:

english

Fichier:

PDF, 579 KB

english, 2011

6

A de novo designed protein–protein interface

Po-Ssu Huang, John J. Love, Stephen L. Mayo

Journal:

Protein Science

Année:

2007

Langue:

english

Fichier:

PDF, 189 KB

english, 2007

7

Refocussing Antibody Responses by Chemical Modification of Vaccine Antigens

Schiffner, Torben, Leonavicius, Karolis, Schuster, Heiko, Kim, Helen J., Kong, Leopold, Saliba, Regis, Brod, Florian, Wegmann, Frank, Huang, Po-Ssu, Stewart-Jones, Guillaume B., Schief, William R., Wa

Journal:

AIDS Research and Human Retroviruses

Année:

2014

Langue:

english

Fichier:

PDF, 85 KB

english, 2014

8

A General Computational Approach for Repeat Protein Design

Parmeggiani, Fabio, Huang, Po-Ssu, Vorobiev, Sergey, Xiao, Rong, Park, Keunwan, Caprari, Silvia, Su, Min, Seetharaman, Jayaraman, Mao, Lei, Janjua, Haleema, Montelione, Gaetano T., Hunt, John, Baker,

Journal:

Journal of Molecular Biology

Année:

2015

Langue:

english

Fichier:

PDF, 2.86 MB

english, 2015

9

Computational De Novo Design of a Self-Assembling Peptide with Predefined Structure

Kaltofen, Sabine, Li, Chenge, Huang, Po-Ssu, Serpell, Louise C., Barth, Andreas, André, Ingemar

Journal:

Journal of Molecular Biology

Année:

2015

Langue:

english

Fichier:

PDF, 1.68 MB

english, 2015

10

Control of repeat-protein curvature by computational protein design

Park, Keunwan, Shen, Betty W, Parmeggiani, Fabio, Huang, Po-Ssu, Stoddard, Barry L, Baker, David

Journal:

Nature Structural and Molecular Biology

Année:

2015

Langue:

english

Fichier:

PDF, 2.46 MB

english, 2015

11

Using Molecular Dynamics Simulations as an Aid in the Prediction of Domain Swapping of Computationally Designed Protein Variants

Mou, Yun, Huang, Po-Ssu, Thomas, Leonard M., Mayo, Stephen L.

Journal:

Journal of Molecular Biology

Année:

2015

Langue:

english

Fichier:

PDF, 963 KB

english, 2015

12

De novo design of a four-fold symmetric TIM-barrel protein with atomic-level accuracy

Huang, Po-Ssu, Feldmeier, Kaspar, Parmeggiani, Fabio, Fernandez Velasco, D Alejandro, Höcker, Birte, Baker, David

Journal:

Nature Chemical Biology

Année:

2015

Langue:

english

Fichier:

PDF, 2.44 MB

english, 2015

13

A Designed Protein Interface That Blocks Fibril Formation

Shukla, Ushma J., Marino, Heather, Huang, Po-Ssu, Mayo, Stephen L., Love, John J.

Journal:

Journal of the American Chemical Society

Année:

2004

Langue:

english

Fichier:

PDF, 141 KB

english, 2004

14

Computational design and experimental verification of a symmetric protein homodimer

Mou, Yun, Huang, Po-Ssu, Hsu, Fang-Ciao, Huang, Shing-Jong, Mayo, Stephen L.

Journal:

Proceedings of the National Academy of Sciences

Année:

2015

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2015

15

Design of a hyperstable 60-subunit protein icosahedron

Hsia, Yang, Bale, Jacob B., Gonen, Shane, Shi, Dan, Sheffler, William, Fong, Kimberly K., Nattermann, Una, Xu, Chunfu, Huang, Po-Ssu, Ravichandran, Rashmi, Yi, Sue, Davis, Trisha N., Gonen, Tamir, Kin

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 7.07 MB

english, 2016

16

Corrigendum: Design of a hyperstable 60-subunit protein icosahedron

Hsia, Yang, Bale, Jacob B., Gonen, Shane, Shi, Dan, Sheffler, William, Fong, Kimberly K., Nattermann, Una, Xu, Chunfu, Huang, Po-Ssu, Ravichandran, Rashmi, Yi, Sue, Davis, Trisha N., Gonen, Tamir, Kin

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 40 KB

english, 2016

17

A computationally engineered RAS rheostat reveals RAS–ERK signaling dynamics

Rose, John C, Huang, Po-Ssu, Camp, Nathan D, Ye, Jordan, Leidal, Andrew M, Goreshnik, Inna, Trevillian, Bridget M, Dickinson, Miles S, Cunningham-Bryant, Daniel, Debnath, Jayanta, Baker, David, Wolf-Y

Journal:

Nature Chemical Biology

Année:

2016

Langue:

english

Fichier:

PDF, 2.52 MB

english, 2016

18

Designing repeat proteins: a modular approach to protein design

Parmeggiani, Fabio, Huang, Po-Ssu

Journal:

Current Opinion in Structural Biology

Année:

2017

Langue:

english

Fichier:

PDF, 1.89 MB

english, 2017

19

Multi-Scale Structural Analysis of Proteins by Deep Semantic Segmentation

Eguchi, Raphael R, Huang, Po-Ssu, Valencia, Alfonso

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 814 KB

english, 2019

20

Structure and Functional Binding Epitope of V-domain Ig Suppressor of T Cell Activation

Mehta, Nishant, Maddineni, Sainiteesh, Mathews, Irimpan I., Andres Parra Sperberg, R., Huang, Po-Ssu, Cochran, Jennifer R.

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 2.71 MB

english, 2019

21

Harnessing Human Neural Networks for Protein Design

Huang, Po-Ssu, Thompson, Kirsten A.

Journal:

Année:

2019

Fichier:

PDF, 926 KB

2019

22

Computational design of closely related proteins that adopt two well-defined but structurally divergent folds

Wei, Kathy Y., Moschidi, Danai, Bick, Matthew J., Nerli, Santrupti, McShan, Andrew C., Carter, Lauren P., Huang, Po-Ssu, Fletcher, Daniel A., Sgourakis, Nikolaos G., Boyken, Scott E., Baker, David

Journal:

Proceedings of the National Academy of Sciences

Année:

2020

Fichier:

PDF, 2.52 MB

2020

23

Engineering a potent receptor superagonist or antagonist from a novel IL-6 family cytokine ligand

Kim, Jun W., Marquez, Cesar P., Sperberg, R. Andres Parra, Wu, Jiaxiang, Bae, Won G., Huang, Po-Ssu, Sweet-Cordero, E. Alejandro, Cochran, Jennifer R.

Journal:

Proceedings of the National Academy of Sciences

Année:

2020

Fichier:

PDF, 1.66 MB

2020

24

Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion

Caldwell, Shane J., Haydon, Ian C., Piperidou, Nikoletta, Huang, Po-Ssu, Bick, Matthew J., SjÃ¶strÃ¶m, H. Sebastian, Hilvert, Donald, Baker, David, Zeymer, Cathleen

Journal:

Proceedings of the National Academy of Sciences

Année:

2020

Fichier:

PDF, 1.94 MB

2020